NADH:ubiquinone reductase (Na -transporting) - définition. Qu'est-ce que NADH:ubiquinone reductase (Na -transporting)
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Qu'est-ce (qui) est NADH:ubiquinone reductase (Na -transporting) - définition

ENZYME OF THE RESPIRATORY CHAIN CONSISTING OF SEVERAL POLYPEPTIDE CHAINS AND L-SHAPED, WITH A HORIZONTAL ARM LYING IN THE MEMBRANE AND A VERTICAL ARM THAT PROJECTS INTO THE MATRIX.
Complex I; Nadh dehydrogenase; Complex 1; Mitochondrial complex I; EC 1.6.5.3; NADH:ubiquinone reductase (H+-translocating); NADH dehydrogenase (ubiquinone); NADH:ubiquinone reductase; NADH:ubiquinone oxidoreductase (H+-translocating)
  • NADH Dehydrogenase Mechanism: 
1. The seven primary iron sulfur centers serve to carry electrons from the site of NADH dehydration to ubiquinone. Note that N7 is not found in eukaryotes.

2. There is a reduction of ubiquinone (CoQ) to ubiquinol (CoQH<sub>2</sub>).

3. The energy from the redox reaction results in conformational change allowing hydrogen ions to pass through four transmembrane helix channels.

NADH:ubiquinone reductase (Na+-transporting)         
CLASS OF ENZYMES
EC 1.6.5.8; NADH:ubiquinone oxidoreductase (Na+-translocating)
NADH:ubiquinone reductase (Na+-transporting) ( is an enzyme with systematic name NADH:ubiquinone oxidoreductase (Na+-translocating). In bacteria, three different types of respiratory NADH:quinone oxidoreductases (NQr) have been described: the electrogenic complex I, also called NDH I in bacteria, the non-electrogenic NADH:quinone oxidoreductases (NDH II), and the Na+-translocating NADH:quinone oxidoreductases Na+-NQr.
Na+-transporting two-sector ATPase         
CLASS OF ENZYMES
EC 3.6.3.15; ATP phosphohydrolase (Na+-transporting)
In enzymology, a Na+-transporting two-sector ATPase () is an enzyme that catalyzes the chemical reaction
Na Na Hey Hey Kiss Him Goodbye         
1969 SINGLE BY STEAM
Kiss Him Goodbye; Na Na Hey Hey (Kiss Him Goodbye); Na na hey hey; Sha-Na-Na-Na (Na Na Hey Hey Kiss Him Goodbye); Na Na Na Hey Hey Hey; Na Na Na Na Hey Hey
"Na Na Hey Hey Kiss Him Goodbye" is a 1969 song written and recorded by Paul Leka, Gary DeCarlo and Dale Frashuer, attributed to a then-fictitious band they named "Steam". It was released under the Mercury subsidiary label Fontana and became a number one pop single on the Billboard Hot 100 in late 1969, and remained on the charts in early 1970.

Wikipédia

Respiratory complex I

Respiratory complex I, EC 7.1.1.2 (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans. It catalyzes the transfer of electrons from NADH to coenzyme Q10 (CoQ10) and translocates protons across the inner mitochondrial membrane in eukaryotes or the plasma membrane of bacteria.

This enzyme is essential for the normal functioning of cells, and mutations in its subunits lead to a wide range of inherited neuromuscular and metabolic disorders. Defects in this enzyme are responsible for the development of several pathological processes such as ischemia/reperfusion damage (stroke and cardiac infarction), Parkinson's disease and others.